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Study: Is the Opioid Crisis Response Overlooking Women?

Study: Is the Opioid Crisis Response Overlooking Women?

CONNECTICUT Women’s Health Research at Yale is calling on a government committee to revise its report on a coordinated response to the opioid epidemic so that it reflects the unique needs of women.

In a commentary published in the peer-reviewed journal Biology of Sex Differences, WHRY Director Carolyn M. Mazure, Ph.D., and Jill Becker, Ph.D., chair of the Biopsychology Area of the University of Michigan Psychology Department, detailed the laboratory, clinical and epidemiological evidence showing the need for the report to endorse and encourage the research of sex and gender differences. They argued such data is necessary to generate gender-based interventions that more fully address the opioid epidemic.

“All data must be reported by sex and gender so that gender-specific treatment and prevention strategies derived from this research are provided to practitioners and the public,” the authors said. “We encourage biomedical researchers and clinical care providers, as well as the public, to insist that a successful response to the opioid crisis should highlight the importance of understanding sex and gender differences in the current opioid epidemic.”

Mazure and Becker noted that the draft report of the White House National Science and Technology Council’s Fast-Track Action Committee (FTAC) created to respond to the opioid crisis does include important concerns about maternal and neonatal exposure to opioids. But they said the draft, released in October, overlooks significant and growing data on sex and gender differences in opioid use disorder (OUD). For example, they wrote that women are more likely than men to be prescribed and use opioid analgesics, and females and males experience pain and the effects of opioids differently.

In addition, women more quickly develop addictions after first using addictive substances, and women are more likely than men to relapse after a quit attempt.

The authors also described how women with opioid addiction are more likely than men to have experienced early trauma and have been diagnosed with depression. And women with opioid addiction suffer greater functional impairment in their lives, impacting their ability to work, secure steady housing, and — because women are more often family caretakers — avoid negative effects on children.

“Our experimental models will not begin to yield the desired information until they employ appropriate models that include both females and males, and our clinical and epidemiological investigations will not uncover needed data until both women and men are studied,” the authors said. “A successful response to the opioid crisis will only be found when scientists, practitioners and the public incorporate the essential importance of understanding sex and gender differences into the solution for OUD.”

Posted in: Opioid

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Public Restrooms Become Ground Zero in the Opioid Epidemic

Public Restrooms Become Ground Zero in the Opioid Epidemic

A man named Eddie threaded through the midafternoon crowd in Cambridge, Mass. He was headed for a sandwich shop, the first stop on a tour of public bathrooms.

“I know all the bathrooms that I can and can’t get high in,” said Eddie, 39, pausing in front of the shop’s plate-glass windows, through which we can see a bathroom door.

Eddie, whose last name we’re not including because he uses illegal drugs, knows which restrooms along busy Massachusetts Avenue he can enter, at what hours and for how long. Several restaurants, offices and a social services agency in this neighborhood have closed their restrooms in recent months, but not this sandwich shop.

“With these bathrooms here, you don’t need a key. If it’s vacant, you go in. And then the staff just leaves you alone,” Eddie said. “I know so many people who get high here.”

At the fast-food place right across the street, it’s much harder to get in and out.

“You don’t need a key, but they have a security guard that sits at the little table by the door, directly in front of the bathroom,” Eddie said. Some guards require a receipt for admission to the bathroom, he said, but you can always grab one from the trash.

A chain restaurant a few stores down has installed bathroom door locks opened by a code that you get at the counter. But Eddie and his friends just wait by the door until a customer goes into the restroom, then grab the door and enter as the customer leaves.

“For every 10 steps they use to safeguard against us doing something, we’re going to find 15 more to get over on their 10. That’s just how it is. I’m not saying that’s right, that’s just how it is,” Eddie said.

Eddie is homeless and works at a restaurant. Public bathrooms are among the few places where he can find privacy to inject heroin. He says he doesn’t use the drug often these days. Eddie is on methadone, which curbs his craving for heroin, and he says he now uses the drug only occasionally to be social with friends.

He understands why restaurant owners are unnerved.

“These businesses, primarily, are like family businesses; middle-class people coming in to grab a burger or a cup of coffee. They don’t expect to find somebody dead,” Eddie said. “I get it.”

Managing Public Bathrooms Is ‘A Tricky Thing’

Many businesses don’t know what to do. Some have installed low lighting — blue light, in particular — to make it difficult for people who use injected drugs to find a vein.

The bathrooms at 1369 Coffee House, in the Central Square neighborhood of Cambridge, are open for customers who request the key code from staff at the counter. The owner, Joshua Gerber, has done some remodeling to make the bathrooms safer. There’s a metal box in the wall next to his toilet for needles and other things that clog pipes. And Gerber removed the dropped ceilings in his bathrooms after noticing things tucked above the tiles.

“We’d find needles or people’s drugs,” Gerber said. “It’s a tricky thing, managing a public restroom in a big, busy square like Central Square where there’s a lot of drug use.”

Gerber and his staff have found several people on the bathroom floor in recent years, not breathing.

“It’s very scary,” Gerber said. His eyes drop briefly. “In an ideal world, users would have safe places to go [where] it didn’t become the job of a business to manage that and to look after them and make sure that they were OK.”

There are such public safe-use places in Canada and some European countries, but not in the U.S., at least not yet. So Gerber is taking the unusual step of training his baristas to use naloxone, the drug that reverses most opioid overdoses. He sent a training invitation email to all employees recently. Within 10 minutes, he had about 25 replies.

“Mostly capital ‘Yes!! I’ll be there for sure!’ ‘Count me in!’” Gerber recalled with a grin. “You know, [they were] just thrilled to figure out how they might be able to save a life.”

Safe Spaces and Hospital Bathrooms

Last fall, a woman overdosed in a bathroom in the main lobby of Massachusetts General Hospital in Boston. Luckily, naloxone has become standard equipment for security guards at many hospitals in the Boston area, including that one.

“I carry it on me every day, it’s right here in a little pouch,” said Ryan Curran, a police and security operations manager at the hospital, pulling a small black bag out of his suit jacket pocket.

The woman who overdosed survived, as have seven or eight people who overdosed in the bathrooms since Curran’s team started carrying naloxone in the past 12 to 18 months.

“It’s definitely relieving when you see someone breathing again when two, three minutes beforehand they looked lifeless,” Curran said. “A couple of pumps of the nasal spray and they’re doing better. It’s pretty incredible.”

Massachusetts General Hospital began training security guards after emergency room physician Dr. Ali Raja realized that the hospital’s bathrooms had become a haven for some of his overdose patients.

“There’s an understanding that if you overdose in and around a hospital that you’re much more likely to be able to be treated,” Raja said, “and so we’re finding patients in our restrooms, we’re finding patients in our lobbies who are shooting up or taking their prescription pain medications.”

Many businesses, including hospitals and clinics, don’t want to talk about overdoses within their buildings. Curran wants to be sure the hospital’s message about drug use is clear.

“We don’t want to promote, obviously, people coming here and using it, but if it’s going to happen, then we’d like to be prepared to help them and save them and get them to the [Emergency Department] as fast as possible,” Curran said.

Speed is critical, especially now, when heroin is routinely mixed with the much more potent opioid, fentanyl. Some clinics and restaurants check on bathroom users by having staff knock on the door after 10 or 15 minutes, but fentanyl can deprive the brain of oxygen and cause death within that window. One clinic has installed an intercom and requires people to respond. Another has designed a reverse-motion detector that sets off an alarm if there’s no movement in the bathroom.

Limited Public Discussion

There’s very little discussion of the problem in public, says Dr. Alex Walley, director of the Addiction Medicine Fellowship Program at Boston Medical Center.

“It’s against federal and state law to provide a space where people can use [illegal drugs] knowingly, so that is a big deterrent from people talking about this problem,” he said.

Without some guidance, more libraries, town halls and businesses are closing their bathrooms to the public. That means more drug use, injuries and discarded needles in parks and on city streets.

In the area around Boston Medical Center, wholesalers, gas station owners and industrial facilities are looking into renting portable bathrooms.

“They’re very concerned for their businesses,” said Sue Sullivan, director of the Newmarket Business Association, which represents 235 companies and 28,000 employees in Boston. “But they don’t want to just move the problem. They want to solve the problem.”

Walley and other physicians who work with addiction patients say there are lots of ways to make bathrooms safer for the public and for drug users. A model restroom would be clean and well-lit with stainless-steel surfaces, and few cracks and crevices for hiding drug paraphernalia. It would have a biohazard box for needles and bloodied swabs. It would be stocked with naloxone and perhaps sterile water. The door would open out so that a collapsed body would not block entry. It would be easy to unlock from the outside. And it would be monitored, preferably by a nurse or EMT.

There are Very Few Bathrooms that Fit this Model in the U.S.

Some doctors, nurses and public health workers who help addiction patients argue any solution to the opioid crisis will need to include safe injection sites, where drug users can get high with medical supervision.

“There are limits to better bathroom management,” said Daniel Raymond, deputy director for policy and planning at the New York-based Harm Reduction Coalition. If communities like Boston start to reach a breaking point with bathrooms, “having dedicated facilities like safer drug consumption spaces is the best bet for a long-term structural solution that I think a lot of business owners could buy into.”

Maybe. No business groups in Massachusetts have come out in support of such spaces yet.

By Martha Bebinger, WBUR | This story is part of a partnership that includes WBUR, NPR and Kaiser Health News. Kaiser Health News, a nonprofit health newsroom whose stories appear in news outlets nationwide, is an editorially independent part of the Kaiser Family Foundation.

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Research: Physician Shortage Likely to Have Severe Impact on Patient Care

Research: Physician Shortage Likely to Have Severe Impact on Patient Care

The United States continues to face a projected physician shortage over the next decade, creating a real risk to patient care, according to new data released by the Association of American Medical Colleges. The latest projections continue to align with previous estimates, showing a projected shortage of between 40,800 and 104,900 doctors.

For the third consecutive year, the Life Science division of the global information company, IHS Markit, conducted a study of physician supply and demand on behalf of the AAMC, modeling a wide range of health care and policy scenarios, such as payment and delivery reform, increased use of advanced practice nurses and physician assistants, and delays in physician retirements. This year’s report extended the date of the projections by five years, from 2025 to 2030, to account for the time needed to train a physician who would start medical school in 2017. The report also includes an expanded section modeling the additional demand for physicians that would be generated by health care utilization equity.

“The nation continues to face a significant physician shortage. As our patient population continues to grow and age, we must begin to train more doctors if we wish to meet the health care needs of all Americans,” said AAMC President and CEO Darrell G. Kirch, M.D.

The report aggregates the shortages in four broad categories: primary care, medical specialties, surgical specialties, and other specialties. By 2030, the study estimates a shortfall of between 7,300 and 43,100 primary care physicians. Non-primary care specialties are expected to experience a shortfall of between 33,500 and 61,800 physicians.

These findings are largely consistent with the 2015 and 2016 reports. In particular, the supply of surgical specialists is expected to remain level, while demand increases. The study also finds that the numbers of new primary care physicians and other medical specialists are not keeping pace with the health care demands of a growing and aging population.

“By 2030, the U.S. population of Americans aged 65 and older will grow by 55 percent, which makes the projected shortage especially troubling,” Kirch said. “As patients get older, they need two to three times as many services, mostly in specialty care, which is where the shortages are particularly severe.”

Expanding on last year’s findings, the new report also includes an analysis of the needs and health care utilization of underserved populations. These data show that if the barriers to utilization were removed for these patients, and all Americans accessed health care at the same levels as insured, non-Hispanic white populations, the United States would have needed up to 96,800 doctors in 2015. Nearly three-quarters of those physicians would be needed in metropolitan areas. This figure is in addition to the projected workforce shortage based on current practice patterns.

“Not only do these utilization equity data highlight the need for the nation to train more doctors, they also demonstrate the importance of a diverse health care workforce. Many of those who underutilize health care — despite their need — are from racial and ethnic minority backgrounds,” Kirch said. “A diverse and culturally competent workforce will enable us to provide the care all Americans need and deserve.”

To help alleviate the physician shortage, the AAMC supports a multipronged solution, including expanding medical school class size, innovating in care delivery and team-based care, making better use of technology, and increasing federal support for an additional 3,000 new residency positions per year over the next five years.

“We urge Congress to approve a modest increase in federal support for new doctors,” Kirch said. “Expanded federal support, along with all medical schools and teaching hospitals working to enhance education and improve care delivery, would be a measured approach to solving what could be a dangerous health care crisis.”

The Association of American Medical Colleges is a not-for-profit association dedicated to transforming health care through innovative medical education, cutting-edge patient care, and groundbreaking medical research. Its members comprise all 147 accredited U.S. and 17 accredited Canadian medical schools; nearly 400 major teaching hospitals and health systems, including 51 Department of Veterans Affairs medical centers; and more than 80 academic societies. Through these institutions and organizations, the AAMC serves the leaders of America’s medical schools and teaching hospitals and their nearly 160,000 faculty members, 83,000 medical students, and 115,000 resident physicians. Additional information about the AAMC and its member medical schools and teaching hospitals is available at www.aamc.org.

Posted in: Research

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